Kwaliteitsbewaking Klinische Geneesmiddelanalyse en Toxicologie

Concentration tests and controls.

KKGT / Programma’s / Antimicrobiële middelen / Concentration tests and controls

Concentration tests 2020

Components Unit Round 2020.1A Round 2020.1B Round 2020.2A Round 2020.2B Round 2020.3A Round 2020.3B Round 2020.4A Round 2020.4B
Amikacin mg/l 2,99  20,13  4,73  20,20 35,66 4,51
Gentamicin mg/l  2,51  14,93  29,86  1,007  22,49  0,302
Methotrexate µmol/l  19,84  0,990  0,0495  0,199 9,94  0,600
Tobramycin mg/l  0,942 30,09  2,82  22,64 18,88  –
Vancomycin mg/l  14,65 2,93  19,49  7,83  9,79 39,10

 

Concentration tests 2019

Components Unit Round 2019.1.1 Round 2019.1.2 Round 2019.2.1 Round 2019.2.2 Round 2019.3.1 Round 2019.3.2 Round 2019.4.1 Round 2019.4.2
Amikacin mg/l 2,08 48,03 4,61 20,54 36,20 4,63 48,17 16,41
Gentamicin mg/l 3,17 15,28 29,33 1,03 23,03  0,309  3,68 8,90
Methotrexate µmol/l 19,40 0,964  1,41 0,194  7,75  0,581 0,396 3,88
Tobramycin mg/l  41,09  2,04  29,40  0,822  20,52  0  10,24 0,410
Vancomycin mg/l 19,52  2,99  20,27  7,90  9,87  37,00  24,62  7,89

 

Concentration tests 2018

Components Unit Round 2018.1.1 Round 2018.1.2 Round 2018.2.1 Round 2018.2.2 Round 2018.3.1 Round 2018.3.2 Round 2018.4.1 Round 2018.4.2
Amikacin mg/l  1,91 47,82 4,76 23,87  59,42  4,29 35,71 0,286
Gentamicin mg/l 0,395  21,90  14,83  0,984  32,66 1,97  3,27  8,53
Methotrexate µmol/l  9,92  0,987  1,18  0,190  7,88  2,97  0,782  2,57
Tobramycin mg/l 40,78 2,03  32,46  0,826  30,38  7,11  10,15  2,85
Vancomycin mg/l  24,98 15,10  76,70  5,00  9,80  30,72  24,86  7,69

 

Concentration tests 2017

Components Unit Round 2017.1.1 Round 2017.1.2 Round 2017.2.1 Round 2017.2.2 Round 2017.3.1 Round 2017.3.2 Round 2017.4.1 Round 2017.4.2
Amikacin mg/l 19,81 0  11,89 5,94 59,70 3,96 29,73 3,05
Gentamicin mg/l 25,02 0  10,01  1,50  37,70 6,02  25,03  0,496
Methotrexate µmol/l 1,19 0 7,44  0,938  4,98 0,191  3,97  0,595
Tobramycin mg/l 26,10 0 10,44 1,57  39,33  6,28  26,12  0,522
Vancomycin mg/l 0 4,87 35,95  4,89  7,65  57,63  9,64  21,58

Concentration tests 2016

Components Unit Round 2016.1.1 Round 2016.1.2 Round 2016.2.1 Round 2016.2.2 Round 2016.3.1 Round 2016.3.2 Round 2016.4.1 Round 2016.4.2
Amikacin mg/l 1,99 19,94 5,14  30,73  7,93 50,77 11,86 63,64
Gentamicin mg/l 0,484 10,78 1,35 13,15 0,189 16,72  12,29  4,69
Methotrexate µmol/l  0,489 9,81 0,0986 4,91 0,0490 48,67  0,967  97,63
Tobramycin mg/l 0,292 11,50 16,63 0,796  8,36 3,46  2,13  34,69
Vancomycin mg/l 8,10 24,22 2,44 11,77  11,14 24,05  35,85  24,12

Concentration tests 2015

Components Unit Round 2015.1.1 Round 2015.1.2 Round 2015.2.1 Round 2015.2.2 Round 2015.3.1 Round 2015.3.2 Round 2015.4.1 Round 2015.4.2
Amikacin mg/l  3,46  29,37  2,45  19,69  5,40 29,32  5,87  39,09
Gentamicin mg/l  9,82  1,19  8,33  3,62  2,90  24,35  7,87  2,84
Methotrexate µmol/l 0,295  1,18  0,148  2,96  0,0492  3,95  0,394  4,94
Tobramycin mg/l  12,02  2,40  7,81  1,69  9,02  2,79  17,78  0,599
Vancomycin mg/l  11,84  44,25  14,79  8,90  44,39  36,88  5,89  29,50

Concentration control (matrix: lyophilised human serum)

Components Weighed-in value
Unit 2020 2019 2018 2017 2016 2015 2014
Amikacin mg/l 10,45 10,33 9,92 9,80 9,91 9,76 9,72
Gentamicin mg/l  5,27 5,25 5,45 4,95 4,90 4,86 5,37
Methotrexate µmol/l  1,05 0,995 0,987 0,981 0,950 0,986 0,992
Tobramycin mg/l  5,31 5,27 5,07 5,17 5,06 4,94 5,03
Vancomycin mg/l  15,49 14,78 15,35 14,23 14,08 14,72 14,37
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