Kwaliteitsbewaking Klinische Geneesmiddelanalyse en Toxicologie

Concentration tests and controls.

KKGT / Programma’s / Antischimmel middelen / Concentration tests and controls

Concentration tests 2018

Components Unit Round 2018.1 Round 2018.2 Round 2018.3 Round 2018.4
Fluconazol mg/l
Flucytosine mg/l
Itraconazol mg/l
Hydroxy-Itraconazol mg/l
Posaconazol mg/l
Voriconazol mg/l

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Concentration tests 2017

Components Unit Round 2017.1 Round 2017.2 Round 2017.3 Round 2017.4
Fluconazol mg/l 10,13  25,26  3,01 40,32
Flucytosine mg/l 16,18  76,85  26,70  92,01
Itraconazol mg/l 0,942  1,88  1,12  5,63
Hydroxy-Itraconazol mg/l 0,387  1,93  1,44  3,86
Posaconazol mg/l 2,58  4,12  0,511  2,06
Voriconazol mg/l 0,193  3,23  1,20  5,37

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Concentration tests 2016

Components Unit Round 2016.1 Round 2016.2 Round 2016.3 Round 2016.4
Fluconazol mg/l  1,98  33,07 9,89  59,26
Flucytosine mg/l 11,54  72,20 28,78  119,8
Itraconazol mg/l 1,08 3,36 2,68  4,02
Hydroxy-Itraconazol mg/l 1,25  3,14  1,88  3,75
Posaconazol mg/l  0,394  1,32  0,295 3,27
Voriconazol mg/l 1,10 7,85  0,0986  0,821

Concentration tests 2015

Components Unit Round 2015.1 Round 2015.2 Round 2015.3 Round 2015.4
Fluconazol mg/l  2,98  16,58  6,56  19,87
Flucytosine mg/l  18,97  65,90  14,08  52,63
Itraconazol mg/l  0,507  4,22  0,835  5,27
Hydroxy-Itraconazol mg/l  0,551  3,06  1,09  3,82
Posaconazol mg/l  2,45  3,68  0,486  1,84
Voriconazol mg/l  8,75  13,13  0,303  4,37

Concentration control (matrix: liquid human serum)

Components Weighed-in value
Unit 2018 2017 2016 15002 2015 2014
Fluconazol mg/l 5,94 5,67 5,95 6,06 6,03 5,89
Flucytosine mg/l 63,85 57,54 60,41 58,78 59,95 59,81
Itraconazol mg/l 1,09 1,06 0,996 1,03 0,960 1,03
Hydroxy-Itraconazol mg/l 1,04 1,09 0,990 0,958 1,04 1,03
Posaconazol mg/l 2,15 1,93 1,98 2,01 1,95 2,02
Voriconazol mg/l 3,22 3,22 3,04 3,00 2,99 3,07

 

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